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Seek and Destroy is a side mission in InFamous 2.
The mission starts when a Rebel approaches Cole and reports that three Icemen were caught spying on them, and that they needed to be taken out before they can report back to their base. Cole must pursue the Ice Soldiers and take them out before they can escape. The mission is complete when all of the Ice Soldiers are defeated.
Upon completion, Cole receives 100 XP and slightly reduces enemy activity in New Marais.